Antipsychotics

DESCRIPTION

Antipsychotics are essential in the treatment of schizophrenia, bipolar disorder, severe depression with psychotic features, and acute agitation. These medications primarily work by blocking dopamine receptors, thereby reducing psychotic symptoms such as hallucinations, delusions, and disorganized thinking.

First-Generation (Typical) Antipsychotics: (Haloperidol, Chlorpromazine, Fluphenazine) – Effective in managing positive symptoms of psychosis but carry a higher risk of extrapyramidal symptoms (EPS) such as rigidity, tremors, and tardive dyskinesia.

Second-Generation (Atypical) Antipsychotics: (Aripiprazole, Olanzapine, Quetiapine, Risperidone) – Preferred for long-term treatment due to a lower risk of movement disorders and broader efficacy across both positive and negative symptoms. However, they may increase the risk of metabolic side effects.